It is located on Via de’ Macci right off of Piazza Santa Croce. Tabasco club is located just off of Piazza della Signoria in a very small piazza, look the exact address up so you won’t get lost.
It was founded in 1974 in the height of disco. Tabasco is the oldest and most famous gay club in Florence. Gay and Lesbian clubs are hard to search for in any city, so here is a great list of the top clubs in Florence.